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Most cancers showed moderate nuclear immunoreactivity. Several cases of lymphomas, urothelial, gastric and pancreatic cancers displayed strong nuclear positivity. Most cases of breast, prostate, cervical and endometrial cancers were weakly stained or negative.
Cancer cells displayed moderate to strong nuclear positivity.
GENE INFORMATION
Gene name
RBM17 (HGNC Symbol)
Synonyms
MGC14439, SPF45
Description
RNA binding motif protein 17 (HGNC Symbol)
Entrez gene summary
This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009]