Cell atlas - IL36G - The Human Protein Atlas

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IL36G

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	IL36G
Gene description	Interleukin 36, gamma
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	IL36G (HGNC Symbol)
Synonyms	IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1
Description	Interleukin 36, gamma (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
Chromosome	2
Cytoband	q14.1
Chromosome location (bp)	112973203 - 112985665
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136688 (version 83.38)
Entrez gene	56300
UniProt	Q9NZH8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NZH8
Antibodypedia	IL36G antibodies

PROTEIN BROWSER

IL36G-001	IL36G-002	IL36G-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IL36G-001 ENSP00000259205 ENST00000259205	Q9NZH8 [Direct mapping] Interleukin-36 gamma Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001819 [positive regulation of cytokine production] GO:0002437 [inflammatory response to antigenic stimulus] GO:0005125 [cytokine activity] GO:0005149 [interleukin-1 receptor binding] GO:0005615 [extracellular space] GO:0007267 [cell-cell signaling] GO:0019221 [cytokine-mediated signaling pathway] GO:0032755 [positive regulation of interleukin-6 production] GO:0045087 [innate immune response] GO:0045662 [negative regulation of myoblast differentiation] GO:1901740 [negative regulation of myoblast fusion] Show all	169 aa 18.7 kDa	No	0
IL36G-002 ENSP00000365672 ENST00000376489	Q9NZH8 [Direct mapping] Interleukin-36 gamma Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002437 [inflammatory response to antigenic stimulus] GO:0005125 [cytokine activity] GO:0005149 [interleukin-1 receptor binding] GO:0005615 [extracellular space] GO:0007267 [cell-cell signaling] GO:0019221 [cytokine-mediated signaling pathway] GO:0045087 [innate immune response] Show all	134 aa 14.9 kDa	No	0
IL36G-003 ENSP00000411639 ENST00000447128	C9J681 [Direct mapping] Interleukin-36 gamma Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		38 aa 4.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.