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Most cancer tissues showed moderate to strong cytoplasmic immunoreactivity. Seminomas in testis, lymphomas and carcinoids were generally negative while a majority of squamous cell carcinomas, prostate, gastric and renal cancers were weakly stained or negative.
GENE INFORMATION
Gene name
HECW2 (HGNC Symbol)
Synonyms
KIAA1301, NEDL2
Description
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (HGNC Symbol)
MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)