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Cytoplasmic expression in several tissues including exocrine glandular cells, cells in tubules and ovarian follicle cells.
DATA RELIABILITY
Data reliability description
Antibody staining mainly not consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
R-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1; MIM 116806) signaling (Kim et al., 2006 [PubMed 16357527]).[supplied by OMIM, Mar 2008]