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Many testicular cancers and a few cases of melanomas exhibited moderate to strong nucleolar immunoreactivity. The remaining tumors were mainly negative.
GENE INFORMATION
Gene name
RRP1 (HGNC Symbol)
Synonyms
D21S2056E, NNP-1, Nop52, RRP1A
Description
Ribosomal RNA processing 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA. [provided by RefSeq, Jul 2008]