The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Plasma showed distinct immunoreactivity. Most normal tissues displayed moderate cytoplasmic positivity with additional membranous staining in several cases. Bile ducts, islets of Langerhans, follicle cells, decidual cells, spleen and skeletal muscle were negative.
Plasma showed distinct positivity. Normal tissues generally showed weak to moderate cytoplasmic and membranous staining. Lung and renal tubules displayed strong positivity. Bile duct cells, thyroid, renal glomeruli, decidual cells, skeletal muscle and spleen were negative.
Distinct staining was observed in extracellular matrix and plasma. Strong immunoreactivity was observed in membranes and cytoplasm of pneumocytes and alveolar macrophages. Renal tubules, trophoblasts, bladder, breast and endometrium showed cytoplasmic and/or membranous positivity. Normal cells in general displayed weak staining or were negative.