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Several cases of breast and prostate cancers along with a few colorectal, urothelial and pancreatic cancers exhibited moderate to strong cytoplasmic positivity. Remaining tumors were negative.
Rare case of breast cancer displayed strong cytoplasmic staining. Few cases of melanomas, colorectal, breast, thyroid, lung, liver and urothelial cancers were moderately positive. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
SHROOM1 (HGNC Symbol)
Synonyms
APXL2, KIAA1960
Description
Shroom family member 1 (HGNC Symbol)
Entrez gene summary
SHROOM family members play diverse roles in the development of the nervous system and other tissues (Hagens et al., 2006 [PubMed 16615870]).[supplied by OMIM, Mar 2008]