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Weak to moderate membranous and cytoplasmic positivity was observed in most colorectal cancers and a few cases of breast, liver, ovarian and stomach cancers. Most cancer tissues were negative.
GENE INFORMATION
Gene name
OTOGL (HGNC Symbol)
Synonyms
C12orf64, FLJ90579
Description
Otogelin-like (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2012]