Tissue expression of ZRSR2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ZRSR2
Gene description	Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
Protein class	Cancer-related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ZRSR2 (HGNC Symbol)
Synonyms	U2AF1-RS2, U2AF1L2, URP, ZC3H22
Description	Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 (HGNC Symbol)
Entrez gene summary	This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	p22.2
Chromosome location (bp)	15790472 - 15823260
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169249 (version 83.38)
Entrez gene	8233
UniProt	Q15696 (UniProt - Evidence at protein level)
neXtProt	NX_Q15696
Antibodypedia	ZRSR2 antibodies

PROTEIN BROWSER

ZRSR2-001	ZRSR2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZRSR2-001 ENSP00000303015 ENST00000307771	Q15696 [Direct mapping] U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Missense Mutations COSMIC Frameshift Mutations Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000245 [spliceosomal complex assembly] GO:0000398 [mRNA splicing, via spliceosome] GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005689 [U12-type spliceosomal complex] GO:0008380 [RNA splicing] GO:0030628 [pre-mRNA 3'-splice site binding] GO:0046872 [metal ion binding] Show all	482 aa 58 kDa	No	0
ZRSR2-002 ENSP00000369664 ENST00000380308	A6NDW0 [Direct mapping] U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Missense Mutations COSMIC Frameshift Mutations Protein evidence (Ezkurdia et al 2014) Show all	GO:0003723 [RNA binding] GO:0005634 [nucleus] Show all	147 aa 17 kDa	No	0