Cell atlas - GPR173 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GPR173

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	GPR173
Gene description	G protein-coupled receptor 173
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol. In addition localized to the plasma membrane.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)
Additional location	In addition localized to the Plasma membrane (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA003905
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol. In addition localized to the plasma membrane.

Main location

Cytosol (approved)

Additional location

Plasma membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA003905	SH-SY5Y	Cytosol
	HPA003905	U-2 OS	Plasma membrane
	HPA003905	U-2 OS	Cytosol
	HPA003905	U-251 MG	Cytosol

GENE INFORMATION
Gene name	GPR173 (HGNC Symbol)
Synonyms	SREB3
Description	G protein-coupled receptor 173 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues. [provided by RefSeq, Nov 2009]
Chromosome	X
Cytoband	p11.22
Chromosome location (bp)	53049091 - 53080615
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184194 (version 83.38)
Entrez gene	54328
UniProt	Q9NS66 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NS66
Antibodypedia	GPR173 antibodies

PROTEIN BROWSER

GPR173-001	GPR173-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR173-001 ENSP00000331600 ENST00000332582	Q9NS66 [Direct mapping] Probable G-protein coupled receptor 173 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004968 [gonadotropin-releasing hormone receptor activity] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0097211 [cellular response to gonadotropin-releasing hormone] GO:2001223 [negative regulation of neuron migration] Show all	373 aa 41.5 kDa	No	7
GPR173-002 ENSP00000364615 ENST00000375466	J3KPD1 [Direct mapping] Probable G-protein-coupled receptor 173 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	52 aa 5.3 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.