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Most malignancies showed weak to moderate cytoplasmic positivity. Malignant gliomas, renal, gastric and skin cancers were weakly stained or negative.
GENE INFORMATION
Gene name
CHML (HGNC Symbol)
Synonyms
REP-2
Description
Choroideremia-like (Rab escort protein 2) (HGNC Symbol)
Entrez gene summary
The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. [provided by RefSeq, Jul 2008]