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Several cases of ovarian cancers along with few cases of lymphomas, colorectal and endometrial cancers showed moderate to strong cytoplasmic staining. Rare cases of colorectal cancers displayed moderate membranous staining. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
LILRA4 (HGNC Symbol)
Synonyms
CD85g, ILT7
Description
Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 (HGNC Symbol)
Entrez gene summary
This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3). This gene is one of a cluster of highly related genes located at chromosomal region 19q13.4. [provided by RefSeq, Jan 2015]