Cell atlas - C7orf73 - The Human Protein Atlas

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C7orf73

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	C7orf73
Gene description	Chromosome 7 open reading frame 73
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the mitochondria.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA065565
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the mitochondria.

Main location

Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA065565	SH-SY5Y	Mitochondria
	HPA065565	SiHa	Mitochondria
	HPA065565	U-2 OS	Mitochondria

GENE INFORMATION
Gene name	C7orf73 (HGNC Symbol)
Synonyms	PL-5283
Description	Chromosome 7 open reading frame 73 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q33
Chromosome location (bp)	135662496 - 135693418
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000243317 (version 83.38)
Entrez gene	647087
UniProt	E0CX11 (UniProt - Evidence at protein level)
neXtProt	NX_E0CX11
Antibodypedia	C7orf73 antibodies

PROTEIN BROWSER

C7orf73-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C7orf73-001 ENSP00000425996 ENST00000507606	E0CX11 [Direct mapping] Uncharacterized protein C7orf73 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0031966 [mitochondrial membrane] Show all	47 aa 5.3 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.