Tissue expression of P3H4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	P3H4
Gene description	Prolyl 3-hydroxylase family member 4 (non-enzymatic)
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	P3H4 (HGNC Symbol)
Synonyms	LEPREL4, NO55, SC65
Description	Prolyl 3-hydroxylase family member 4 (non-enzymatic) (HGNC Symbol)
Entrez gene summary	This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q21.2
Chromosome location (bp)	41801947 - 41812604
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000141696 (version 83.38)
Entrez gene	10609
UniProt	Q92791 (UniProt - Evidence at protein level)
neXtProt	NX_Q92791
Antibodypedia	P3H4 antibodies

PROTEIN BROWSER

P3H4-001	P3H4-006	P3H4-007	P3H4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
P3H4-001 ENSP00000347649 ENST00000355468	Q92791 [Direct mapping] Synaptonemal complex protein SC65 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000794 [condensed nuclear chromosome] GO:0000795 [synaptonemal complex] GO:0005730 [nucleolus] GO:0007130 [synaptonemal complex assembly] Show all	437 aa 50.4 kDa	Yes	0
P3H4-006 ENSP00000468174 ENST00000592026	K7ERA3 [Direct mapping] Protein P3H4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		221 aa 25.9 kDa	No	0
P3H4-007 ENSP00000464968 ENST00000590496	K7EJ03 [Direct mapping] Synaptonemal complex protein SC65 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		85 aa 9.5 kDa	Yes	0
P3H4-201 ENSP00000377505 ENST00000393928	Q92791 [Direct mapping] Synaptonemal complex protein SC65 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000794 [condensed nuclear chromosome] GO:0005730 [nucleolus] GO:0007130 [synaptonemal complex assembly] Show all	437 aa 50.4 kDa	Yes	0