The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Strong cytoplasmic staining was observed in glandular cells of small intestine and renal tubules. Fallopian tube, respiratory epithelia and cells in glomeruli displayed weak to moderate positivity. Plasma distinctly stained. Remaining normal tissues were negative.
Renal tubules, small intestine, urothelium, oral mucosa along with subset of hepatocytes and Leydig cells showed moderate to strong cytoplasmic positivity. Other normal tissues were generally negative.
Strong cytoplasmic positivity was observed in small intestinal glands and renal tubules. Most remaining normal tissues were negative.
Small intestinal glands, oral mucosa and renal tubules showed strong cytoplasmic positivity. Other normal tissues were in general negative.
Duodenum and small intestine displayed strong cytoplasmic immunoreactivity. Strong membranous staining was noted in subset of urothelia. Renal tubules showed strong granular cytoplasmic and membranous staining. A subset of cells in adrenal displayed strong cytoplasmic and nuclear immunoreactivity while squamous epithelium of oral mucosa showed additional membranous staining. Plasma and extracellular secretions displayed distinct staining. Remaining normal tissues were negative.