The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Leydig cells showed strong cytoplasmic positivity. Subset of glial cells in CNS, ovarian stroma, fallopian tubes, stomach and adrenal glands exhibited moderate immunoreactivity. Additional nuclear staining is seen in molecular layer of cerebellum, gall bladder, exocrine pancreas and gastric glands. Other normal tissues were weakly stained or negative.
Strong cytoplasmic positivity was observed in Leydig cells and in ovarian and endometrial stromal cells. Respiratory epithelia, the gastrointestinal tract, pancreas and adrenal cortex showed moderate cytoplasmic staining. The remaining normal tissues were in general weakly stained or negative.
Normal tissues generally displayed moderate cytoplasmic positivity. Strong staining was observed in exocrine pancreas, Leydig cells and glial cells. Neurons and islets of Langerhans were negative.