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The protein encoded by this gene contains a Src homology-3 (SH3) domain and a sterile alpha motif (SAM), both of which are found in proteins involved in cell signaling. This protein may function as a signaling adapter protein in lymphocytes.[provided by RefSeq, Sep 2009]
O75995 [Direct mapping] SAM and SH3 domain-containing protein 3
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Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0002639 [positive regulation of immunoglobulin production] GO:0002726 [positive regulation of T cell cytokine production] GO:0002821 [positive regulation of adaptive immune response] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0030890 [positive regulation of B cell proliferation] GO:0032729 [positive regulation of interferon-gamma production] GO:0032733 [positive regulation of interleukin-10 production] GO:0032743 [positive regulation of interleukin-2 production] GO:0032753 [positive regulation of interleukin-4 production] GO:0032760 [positive regulation of tumor necrosis factor production] GO:0042102 [positive regulation of T cell proliferation] GO:0043372 [positive regulation of CD4-positive, alpha-beta T cell differentiation] GO:0046622 [positive regulation of organ growth] GO:0048873 [homeostasis of number of cells within a tissue] GO:0051251 [positive regulation of lymphocyte activation]