Expression of ENPP4 in cancer - Summary

CANCER ATLAS

Gene description

Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA016594

GENE INFORMATION
Gene name	ENPP4 (HGNC Symbol)
Synonyms	KIAA0879, NPP4
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	46129993 - 46146699
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000001561 (version 83.38)
Entrez gene	22875
UniProt	Q9Y6X5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y6X5
Antibodypedia	ENPP4 antibodies

PROTEIN BROWSER

ENPP4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ENPP4-001 ENSP00000318066 ENST00000321037	Q9Y6X5 [Direct mapping] Bis(5'-adenosyl)-triphosphatase ENPP4 Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005886 [plasma membrane] GO:0007596 [blood coagulation] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030194 [positive regulation of blood coagulation] GO:0046130 [purine ribonucleoside catabolic process] GO:0046872 [metal ion binding] GO:0047710 [bis(5'-adenosyl)-triphosphatase activity] GO:0070062 [extracellular exosome] Show all	453 aa 51.6 kDa	Yes	1