Tissue expression of MTMR7 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	MTMR7
Gene description	Myotubularin related protein 7
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (cerebral cortex, parathyroid gland)
GTEx:	Tissue enhanced (cerebellum)
FANTOM5:	Group enriched (cerebellum, pituitary gland, caudate, brain, hippocampus, retina)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebral cortex, parathyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebellum)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cerebellum, pituitary gland, caudate, brain, hippocampus, retina)

GENE INFORMATION
Gene name	MTMR7
Synonyms
Description	Myotubularin related protein 7 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Mar 2009]
Chromosome	8
Cytoband	p22
Chromosome location (bp)	17298030 - 17413528
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000003987 (version 83.38)
Entrez gene	9108
UniProt	Q9Y216 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y216
Antibodypedia	MTMR7 antibodies

PROTEIN BROWSER

MTMR7-001	MTMR7-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MTMR7-001 ENSP00000180173 ENST00000180173	Q9Y216 [Direct mapping] Myotubularin-related protein 7 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004725 [protein tyrosine phosphatase activity] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006470 [protein dephosphorylation] GO:0006644 [phospholipid metabolic process] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0016020 [membrane] GO:0016311 [dephosphorylation] GO:0016791 [phosphatase activity] GO:0035335 [peptidyl-tyrosine dephosphorylation] GO:0044281 [small molecule metabolic process] GO:0046855 [inositol phosphate dephosphorylation] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052866 [phosphatidylinositol phosphate phosphatase activity] Show all	660 aa 75.8 kDa	No	0
MTMR7-002 ENSP00000429733 ENST00000521857	Q9Y216 [Direct mapping] Myotubularin-related protein 7 Show all	Predicted intracellular proteins Show all	GO:0004725 [protein tyrosine phosphatase activity] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006470 [protein dephosphorylation] GO:0006644 [phospholipid metabolic process] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0016311 [dephosphorylation] GO:0016791 [phosphatase activity] GO:0035335 [peptidyl-tyrosine dephosphorylation] GO:0044281 [small molecule metabolic process] GO:0052866 [phosphatidylinositol phosphate phosphatase activity] Show all	555 aa 64.7 kDa	No	0