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MEOX1

CANCER ATLAS

Gene description

 Mesenchyme homeobox 1

Protein class

 Disease related genes, Predicted intracellular proteins, Transcription factors

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA045214

GENE INFORMATION

Gene name

 MEOX1 (HGNC Symbol)

Synonyms

 MOX1

Description

 Mesenchyme homeobox 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

 17

Cytoband

 q21.31

Chromosome location (bp)

 43640388 - 43661954

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000005102 (version 83.38)

Entrez gene

 4222

UniProt

 P50221 (UniProt - Evidence at protein level)

neXtProt

 NX_P50221

Antibodypedia

 MEOX1 antibodies

PROTEIN BROWSER
MEOX1-001
MEOX1-002
MEOX1-003
MEOX1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MEOX1-001
ENSP00000321684
ENST00000318579
P50221 [Direct mapping]
Homeobox protein MOX-1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001046 [core promoter sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001757 [somite specification]
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007275 [multicellular organismal development]
GO:0008150 [biological_process]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0060218 [hematopoietic stem cell differentiation]
GO:0061053 [somite development]
GO:0061056 [sclerotome development]
GO:0071837 [HMG box domain binding]
Show all
 254 aa
28 kDa 		No 0
MEOX1-002
ENSP00000449049
ENST00000549132
F8VXS6 [Direct mapping]
Homeobox protein MOX-1
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
Show all
 167 aa
18.5 kDa 		No 0
MEOX1-003
ENSP00000377271
ENST00000393661
P50221 [Direct mapping]
Homeobox protein MOX-1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
Show all
GO:0001046 [core promoter sequence-specific DNA binding]
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0008150 [biological_process]
GO:0043565 [sequence-specific DNA binding]
GO:0060218 [hematopoietic stem cell differentiation]
GO:0061053 [somite development]
GO:0061056 [sclerotome development]
Show all
 139 aa
15.6 kDa 		No 0
MEOX1-201
ENSP00000328678
ENST00000329168
P50221 [Direct mapping]
Homeobox protein MOX-1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
Show all
GO:0001046 [core promoter sequence-specific DNA binding]
GO:0003674 [molecular_function]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007275 [multicellular organismal development]
GO:0008150 [biological_process]
GO:0043565 [sequence-specific DNA binding]
GO:0060218 [hematopoietic stem cell differentiation]
GO:0061053 [somite development]
GO:0061056 [sclerotome development]
Show all
 184 aa
19.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.