Expression of CACNG3 in cancer - Summary

CANCER ATLAS

Gene description

Calcium channel, voltage-dependent, gamma subunit 3

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Melanoma

STAINING SUMMARY

HPA059010

GENE INFORMATION
Gene name	CACNG3
Synonyms
Description	Calcium channel, voltage-dependent, gamma subunit 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy. [provided by RefSeq, Dec 2010]
Chromosome	16
Cytoband	p12.1
Chromosome location (bp)	24255553 - 24362801
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006116 (version 83.38)
Entrez gene	10368
UniProt	O60359 (UniProt - Evidence at transcript level)
neXtProt	NX_O60359
Antibodypedia	CACNG3 antibodies

PROTEIN BROWSER

CACNG3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CACNG3-001 ENSP00000005284 ENST00000005284	O60359 [Direct mapping] Voltage-dependent calcium channel gamma-3 subunit Show all	Transporters Accessory Factors Involved in Transport Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005245 [voltage-gated calcium channel activity] GO:0005886 [plasma membrane] GO:0005891 [voltage-gated calcium channel complex] GO:0006816 [calcium ion transport] GO:0007268 [synaptic transmission] GO:0016021 [integral component of membrane] GO:0016247 [channel regulator activity] GO:0019226 [transmission of nerve impulse] GO:0030666 [endocytic vesicle membrane] GO:0032281 [AMPA glutamate receptor complex] GO:0070588 [calcium ion transmembrane transport] GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity] Show all	315 aa 35.5 kDa	No	4