Cell atlas - ALDH3B1 - The Human Protein Atlas

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ALDH3B1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ALDH3B1
Gene description	Aldehyde dehydrogenase 3 family, member B1
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (A549, CAPAN-2)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (A549, CAPAN-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ALDH3B1 (HGNC Symbol)
Synonyms	ALDH7
Description	Aldehyde dehydrogenase 3 family, member B1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Chromosome	11
Cytoband	q13.2
Chromosome location (bp)	68008578 - 68029282
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006534 (version 83.38)
Entrez gene	221
UniProt	P43353 (UniProt - Evidence at protein level)
neXtProt	NX_P43353
Antibodypedia	ALDH3B1 antibodies

PROTEIN BROWSER

ALDH3B1-001	ALDH3B1-002	ALDH3B1-004	ALDH3B1-006	ALDH3B1-007	ALDH3B1-009	ALDH3B1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ALDH3B1-001 ENSP00000473990 ENST00000342456	P43353 [Direct mapping] Aldehyde dehydrogenase family 3 member B1 A0A024R5D8 [Target identity:100%; Query identity:100%] Aldehyde dehydrogenase Show all	Enzymes ENZYME proteins Oxidoreductases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004028 [3-chloroallyl aldehyde dehydrogenase activity] GO:0004030 [aldehyde dehydrogenase [NAD(P)+] activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006066 [alcohol metabolic process] GO:0006068 [ethanol catabolic process] GO:0006081 [cellular aldehyde metabolic process] GO:0006629 [lipid metabolic process] GO:0006665 [sphingolipid metabolic process] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0030148 [sphingolipid biosynthetic process] GO:0031982 [vesicle] GO:0034599 [cellular response to oxidative stress] GO:0044281 [small molecule metabolic process] GO:0046185 [aldehyde catabolic process] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] Show all	468 aa 51.8 kDa	No	0
ALDH3B1-002 ENSP00000478486 ENST00000614849	P43353 [Direct mapping] Aldehyde dehydrogenase family 3 member B1 A0A024R5D8 [Target identity:100%; Query identity:100%] Aldehyde dehydrogenase Show all	Enzymes ENZYME proteins Oxidoreductases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004028 [3-chloroallyl aldehyde dehydrogenase activity] GO:0004030 [aldehyde dehydrogenase [NAD(P)+] activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006066 [alcohol metabolic process] GO:0006068 [ethanol catabolic process] GO:0006081 [cellular aldehyde metabolic process] GO:0006629 [lipid metabolic process] GO:0006665 [sphingolipid metabolic process] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0030148 [sphingolipid biosynthetic process] GO:0031982 [vesicle] GO:0034599 [cellular response to oxidative stress] GO:0044281 [small molecule metabolic process] GO:0046185 [aldehyde catabolic process] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] Show all	468 aa 51.8 kDa	No	0
ALDH3B1-004 ENSP00000481604 ENST00000617288	P43353 [Direct mapping] Aldehyde dehydrogenase family 3 member B1 A0A024R5K0 [Target identity:100%; Query identity:100%] Aldehyde dehydrogenase Show all	Enzymes ENZYME proteins Oxidoreductases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004028 [3-chloroallyl aldehyde dehydrogenase activity] GO:0004030 [aldehyde dehydrogenase [NAD(P)+] activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006066 [alcohol metabolic process] GO:0006068 [ethanol catabolic process] GO:0006081 [cellular aldehyde metabolic process] GO:0006629 [lipid metabolic process] GO:0006665 [sphingolipid metabolic process] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0030148 [sphingolipid biosynthetic process] GO:0031982 [vesicle] GO:0034599 [cellular response to oxidative stress] GO:0044281 [small molecule metabolic process] GO:0046185 [aldehyde catabolic process] GO:0055114 [oxidation-reduction process] GO:0070062 [extracellular exosome] Show all	431 aa 47.7 kDa	No	0
ALDH3B1-006 ENSP00000484901 ENST00000612297	A0A087X2D4 [Direct mapping] Aldehyde dehydrogenase family 3 member B1 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0016620 [oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor] GO:0055114 [oxidation-reduction process] Show all	351 aa 38.9 kDa	No	0
ALDH3B1-007 ENSP00000478380 ENST00000527514	A0A087WU54 [Direct mapping] Aldehyde dehydrogenase family 3 member B1 Show all	Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0016620 [oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor] GO:0055114 [oxidation-reduction process] Show all	71 aa 8.2 kDa	No	0
ALDH3B1-009 ENSP00000483988 ENST00000617449	A0A087X192 [Direct mapping] Aldehyde dehydrogenase family 3 member B1 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	211 aa 23.3 kDa	No	0
ALDH3B1-201 ENSP00000479948 ENST00000615463	Q9BUJ8 [Direct mapping] ALDH3B1 protein; Aldehyde dehydrogenase family 3 member B1 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	230 aa 25.4 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.