Expression of ARSD in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Arylsulfatase D

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA004694

GENE INFORMATION
Gene name	ARSD
Synonyms
Description	Arylsulfatase D (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y. [provided by RefSeq, Jul 2011]
Chromosome	X
Cytoband	p22.33
Chromosome location (bp)	2903970 - 2929351
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006756 (version 83.38)
Entrez gene	414
UniProt	P51689 (UniProt - Evidence at protein level)
neXtProt	NX_P51689
Antibodypedia	ARSD antibodies

PROTEIN BROWSER

ARSD-001	ARSD-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARSD-001 ENSP00000370546 ENST00000381154	P51689 [Direct mapping] Arylsulfatase D Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004065 [arylsulfatase activity] GO:0005764 [lysosome] GO:0005788 [endoplasmic reticulum lumen] GO:0006665 [sphingolipid metabolic process] GO:0006687 [glycosphingolipid metabolic process] GO:0008152 [metabolic process] GO:0008484 [sulfuric ester hydrolase activity] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	593 aa 64.9 kDa	Yes	1
ARSD-004 ENSP00000409180 ENST00000458014	H7C327 [Direct mapping] Arylsulfatase D Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	159 aa 17.4 kDa	No	0