Tissue expression of LUC7L - Summary - The Human Protein Atlas

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LUC7L

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	LUC7L
Gene description	LUC7-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous nuclear expression.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 1 antibody. HPA069321
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	LUC7L (HGNC Symbol)
Synonyms	hLuc7B1, Luc7, LUC7B1
Description	LUC7-like (HGNC Symbol)
Entrez gene summary	The LUC7L gene may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection (Tufarelli et al., 2001 [PubMed 11170747]).[supplied by OMIM, Mar 2008]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	188969 - 229463
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000007392 (version 83.38)
Entrez gene	55692
UniProt	Q9NQ29 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQ29
Antibodypedia	LUC7L antibodies

PROTEIN BROWSER

LUC7L-001	LUC7L-002	LUC7L-003	LUC7L-007	LUC7L-012	LUC7L-015	LUC7L-016	LUC7L-018	LUC7L-020	LUC7L-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LUC7L-001 ENSP00000337507 ENST00000337351	Q9NQ29 [Direct mapping] Putative RNA-binding protein Luc7-like 1 Q1W6G4 [Target identity:100%; Query identity:100%] LUC7-like (S. cerevisiae); LUC7-like (S. cerevisiae), isoform CRA_g; Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003729 [mRNA binding] GO:0005515 [protein binding] GO:0005685 [U1 snRNP] GO:0006376 [mRNA splice site selection] GO:0042802 [identical protein binding] GO:0071004 [U2-type prespliceosome] Show all	325 aa 38.4 kDa	No	0
LUC7L-002 ENSP00000380885 ENST00000397783	Q9NQ29 [Direct mapping] Putative RNA-binding protein Luc7-like 1 Q1W6G4 [Target identity:100%; Query identity:100%] LUC7-like (S. cerevisiae); LUC7-like (S. cerevisiae), isoform CRA_g; Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003729 [mRNA binding] GO:0005515 [protein binding] GO:0005685 [U1 snRNP] GO:0006376 [mRNA splice site selection] GO:0042802 [identical protein binding] GO:0071004 [U2-type prespliceosome] Show all	325 aa 38.4 kDa	No	0
LUC7L-003 ENSP00000293872 ENST00000293872	Q9NQ29 [Direct mapping] Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003729 [mRNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005685 [U1 snRNP] GO:0006376 [mRNA splice site selection] GO:0042802 [identical protein binding] GO:0045843 [negative regulation of striated muscle tissue development] GO:0050733 [RS domain binding] GO:0071004 [U2-type prespliceosome] Show all	371 aa 43.7 kDa	No	0
LUC7L-007 ENSP00000380882 ENST00000397780	A8MYV2 [Direct mapping] LUC7-like (S. cerevisiae); LUC7-like (S. cerevisiae), isoform CRA_f; Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003729 [mRNA binding] GO:0005685 [U1 snRNP] GO:0006376 [mRNA splice site selection] Show all	272 aa 32.4 kDa	No	0
LUC7L-012 ENSP00000414508 ENST00000443357	B8ZZ09 [Direct mapping] LUC7-like (S. cerevisiae); Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003729 [mRNA binding] GO:0005685 [U1 snRNP] GO:0006376 [mRNA splice site selection] Show all	84 aa 9.5 kDa	No	0
LUC7L-015 ENSP00000406695 ENST00000430864	B8ZZ10 [Direct mapping] LUC7-like (S. cerevisiae); Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003729 [mRNA binding] GO:0005685 [U1 snRNP] GO:0006376 [mRNA splice site selection] Show all	182 aa 21.4 kDa	No	0
LUC7L-016 ENSP00000413033 ENST00000429378	B8ZZ08 [Direct mapping] LUC7-like (S. cerevisiae); Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		170 aa 20.7 kDa	No	0
LUC7L-018 ENSP00000407781 ENST00000442701	H7C2U4 [Direct mapping] Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		60 aa 7.6 kDa	No	0
LUC7L-020 ENSP00000409977 ENST00000428363	B8ZZ12 [Direct mapping] LUC7-like (S. cerevisiae); Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003729 [mRNA binding] GO:0005685 [U1 snRNP] GO:0006376 [mRNA splice site selection] Show all	32 aa 3.8 kDa	No	0
LUC7L-201 ENSP00000485761 ENST00000629543	F2Z322 [Direct mapping] Putative RNA-binding protein Luc7-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		55 aa 6.1 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.