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Colorectal cancer as well as a several pancreatic, gastric, ovarian, breast and prostate cancer showed moderate to strong membranous and cytoplasmic immunoreactivity. Most remaining cancer tissues were in general negative or weakly stained.
GENE INFORMATION
Gene name
TEAD3 (HGNC Symbol)
Synonyms
ETFR-1, TEAD5, TEF-5
Description
TEA domain family member 3 (HGNC Symbol)
Entrez gene summary
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon. [provided by RefSeq, Jul 2008]
Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001085 [RNA polymerase II transcription factor binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0007565 [female pregnancy] GO:0010467 [gene expression] GO:0035329 [hippo signaling] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:1902459 [positive regulation of stem cell population maintenance]