Cell atlas - MYLIP - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MYLIP

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	MYLIP
Gene description	Myosin regulatory light chain interacting protein
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MYLIP (HGNC Symbol)
Synonyms	IDOL, MIR
Description	Myosin regulatory light chain interacting protein (HGNC Symbol)
Entrez gene summary	The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	p22.3
Chromosome location (bp)	16129125 - 16148248
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000007944 (version 83.38)
Entrez gene	29116
UniProt	Q8WY64 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WY64
Antibodypedia	MYLIP antibodies

PROTEIN BROWSER

MYLIP-001	MYLIP-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MYLIP-001 ENSP00000349298 ENST00000356840	Q8WY64 [Direct mapping] E3 ubiquitin-protein ligase MYLIP Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] GO:0005886 [plasma membrane] GO:0006928 [movement of cell or subcellular component] GO:0007399 [nervous system development] GO:0008092 [cytoskeletal protein binding] GO:0008270 [zinc ion binding] GO:0010989 [negative regulation of low-density lipoprotein particle clearance] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0019898 [extrinsic component of membrane] GO:0031648 [protein destabilization] GO:0032803 [regulation of low-density lipoprotein particle receptor catabolic process] GO:0042632 [cholesterol homeostasis] GO:0042787 [protein ubiquitination involved in ubiquitin-dependent protein catabolic process] GO:0045732 [positive regulation of protein catabolic process] GO:0061630 [ubiquitin protein ligase activity] Show all	445 aa 49.9 kDa	No	0
MYLIP-002 ENSP00000008686 ENST00000349606	Q5TIA5 [Direct mapping] E3 ubiquitin-protein ligase MYLIP; Myosin regulatory light chain interacting protein, isoform CRA_b Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005856 [cytoskeleton] GO:0008270 [zinc ion binding] Show all	264 aa 29.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.