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NADK

GENERAL INFORMATION

Gene name

 NADK

Gene description

 NAD kinase

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic and occasional membranous expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

 Uncertain based on 1 antibody.
HPA048909
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NADK (HGNC Symbol)

Synonyms

 FLJ13052

Description

 NAD kinase (HGNC Symbol)

Entrez gene summary

 NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001 [PubMed 11594753]).[supplied by OMIM, Mar 2008]

Chromosome

 1

Cytoband

 p36.33

Chromosome location (bp)

 1751232 - 1780457

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000008130 (version 83.38)

Entrez gene

 65220

UniProt

 O95544 (UniProt - Evidence at protein level)

neXtProt

 NX_O95544

Antibodypedia

 NADK antibodies

PROTEIN BROWSER
NADK-001
NADK-002
NADK-003
NADK-016
NADK-017

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NADK-001
ENSP00000367890
ENST00000378625
O95544 [Direct mapping]
NAD kinase
Show all
Enzymes
   ENZYME proteins
   Transferases
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003951 [NAD+ kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005829 [cytosol]
GO:0006741 [NADP biosynthetic process]
GO:0006766 [vitamin metabolic process]
GO:0006767 [water-soluble vitamin metabolic process]
GO:0008152 [metabolic process]
GO:0016310 [phosphorylation]
GO:0019674 [NAD metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046034 [ATP metabolic process]
GO:0046872 [metal ion binding]
Show all
 591 aa
63.5 kDa 		No 0
NADK-002
ENSP00000344340
ENST00000341991
O95544 [Direct mapping]
NAD kinase
A0A024R058 [Target identity:100%; Query identity:100%]
NAD kinase, isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Transferases
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003951 [NAD+ kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005829 [cytosol]
GO:0006741 [NADP biosynthetic process]
GO:0006766 [vitamin metabolic process]
GO:0006767 [water-soluble vitamin metabolic process]
GO:0008152 [metabolic process]
GO:0016310 [phosphorylation]
GO:0019674 [NAD metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046034 [ATP metabolic process]
GO:0046872 [metal ion binding]
Show all
 446 aa
49.2 kDa 		No 0
NADK-003
ENSP00000341679
ENST00000341426
O95544 [Direct mapping]
NAD kinase
A0A024R058 [Target identity:100%; Query identity:100%]
NAD kinase, isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Transferases
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003951 [NAD+ kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005829 [cytosol]
GO:0006741 [NADP biosynthetic process]
GO:0006766 [vitamin metabolic process]
GO:0006767 [water-soluble vitamin metabolic process]
GO:0008152 [metabolic process]
GO:0016310 [phosphorylation]
GO:0019674 [NAD metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046034 [ATP metabolic process]
GO:0046872 [metal ion binding]
Show all
 446 aa
49.2 kDa 		No 0
NADK-016
ENSP00000462589
ENST00000469045
J3KSP9 [Direct mapping]
NAD kinase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003951 [NAD+ kinase activity]
GO:0016310 [phosphorylation]
Show all
 44 aa
4.8 kDa 		No 0
NADK-017
ENSP00000339727
ENST00000342348
A0A0A0MR98 [Direct mapping]
NAD kinase
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003951 [NAD+ kinase activity]
GO:0006741 [NADP biosynthetic process]
GO:0008152 [metabolic process]
GO:0016310 [phosphorylation]
GO:0019674 [NAD metabolic process]
Show all
 414 aa
45.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.