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IL32

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GENERAL INFORMATION

Gene name

 IL32

Gene description

 Interleukin 32

Protein class

 Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 30
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (HDLM-2, CACO-2)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HDLM-2, CACO-2)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 IL32 (HGNC Symbol)

Synonyms

 NK4, TAIF, TAIFb, TAIFd

Description

 Interleukin 32 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 3065297 - 3082192

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000008517 (version 83.38)

Entrez gene

 9235

UniProt

 P24001 (UniProt - Evidence at protein level)

neXtProt

 NX_P24001

Antibodypedia

 IL32 antibodies

PROTEIN BROWSER
«
IL32-001
IL32-002
IL32-003
IL32-004
IL32-007
IL32-008
IL32-009
IL32-010
IL32-011
IL32-012
IL32-013
IL32-014
IL32-015
IL32-016
IL32-018
IL32-019
IL32-022
IL32-023
IL32-024
IL32-025
IL32-026
IL32-027
IL32-028
IL32-029
IL32-030
IL32-031
IL32-032
IL32-033
IL32-201
IL32-202
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
IL32-001
ENSP00000324742
ENST00000325568
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-002
ENSP00000431775
ENST00000534507
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 234 aa
26.7 kDa 		Yes 0
IL32-003
ENSP00000433177
ENST00000531965
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 178 aa
20.6 kDa 		No 0
IL32-004
ENSP00000380096
ENST00000396887
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 131 aa
14.9 kDa 		No 0
IL32-007
ENSP00000436937
ENST00000529699
C6GKH1 [Direct mapping]
Interleukin-32; Interleukin-32 theta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0006955 [immune response]
Show all
 168 aa
19.4 kDa 		No 0
IL32-008
ENSP00000432218
ENST00000525643
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-009
ENSP00000411958
ENST00000444393
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-010
ENSP00000008180
ENST00000008180
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 168 aa
19.4 kDa 		No 0
IL32-011
ENSP00000446624
ENST00000548652
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 179 aa
20.8 kDa 		No 0
IL32-012
ENSP00000437020
ENST00000529550
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-013
ENSP00000436929
ENST00000530538
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-014
ENSP00000432917
ENST00000533097
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-015
ENSP00000433866
ENST00000525377
E9PIV2 [Direct mapping]
Interleukin-32
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006955 [immune response]
Show all
 221 aa
25.2 kDa 		Yes 0
IL32-016
ENSP00000433747
ENST00000530890
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 168 aa
19.4 kDa 		No 0
IL32-018
ENSP00000380099
ENST00000396890
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 234 aa
26.7 kDa 		Yes 0
IL32-019
ENSP00000431740
ENST00000525228
E9PK07 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006955 [immune response]
Show all
 131 aa
15.4 kDa 		No 0
IL32-022
ENSP00000450364
ENST00000526464
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-023
ENSP00000447979
ENST00000548246
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 148 aa
17 kDa 		No 0
IL32-024
ENSP00000405063
ENST00000440815
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-025
ENSP00000447496
ENST00000551122
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 131 aa
14.9 kDa 		No 0
IL32-026
ENSP00000448354
ENST00000548807
F8VSD2 [Direct mapping]
Interleukin-32
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006955 [immune response]
Show all
 225 aa
25.7 kDa 		Yes 0
IL32-027
ENSP00000432850
ENST00000528163
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-028
ENSP00000447812
ENST00000549213
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 131 aa
14.9 kDa 		No 0
IL32-029
ENSP00000449483
ENST00000548476
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 234 aa
26.7 kDa 		Yes 0
IL32-030
ENSP00000447033
ENST00000552936
F8W1V1 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006955 [immune response]
Show all
 212 aa
24.2 kDa 		No 0
IL32-031
ENSP00000448683
ENST00000552664
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 188 aa
21.7 kDa 		No 0
IL32-032
ENSP00000446978
ENST00000552356
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 168 aa
19.4 kDa 		No 0
IL32-033
ENSP00000449147
ENST00000551513
F8VVN4 [Direct mapping]
Interleukin-32
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006955 [immune response]
Show all
 225 aa
25.7 kDa 		Yes 0
IL32-201
ENSP00000371648
ENST00000382213
P24001 [Direct mapping]
Interleukin-32
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006955 [immune response]
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
Show all
 179 aa
20.8 kDa 		No 0
IL32-202
ENSP00000479701
ENST00000613483
C6GKH1 [Direct mapping]
Interleukin-32; Interleukin-32 theta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0006955 [immune response]
Show all
 168 aa
19.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.