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Most malignant cells showed weak to moderate cytoplasmic and sometimes nuclear staining. Malignant cells in lymphomas, skin, lung and testis cancers were generally negative.
GENE INFORMATION
Gene name
TSPAN9 (HGNC Symbol)
Synonyms
NET-5
Description
Tetraspanin 9 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009]