We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Prostate cancers and malignant carcinoids exhibited moderate to strong cytoplasmic positivity. Weak nuclear positivity was observed in testicular cancers. The remaining malignant cells were generally negative.
GENE INFORMATION
Gene name
SYT7 (HGNC Symbol)
Synonyms
IPCA-7, MGC150517, PCANAP7, SYT-VII
Description
Synaptotagmin VII (HGNC Symbol)
Entrez gene summary
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]