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Several cases of liver cancers showed moderate cytoplasmic and nuclear staining while lung cancers along with several cases of thyroid cancers, occasional cases of gliomas, melanomas, endometrial, stomach, urothelial and pancreatic cancers displayed moderate nuclear positivity. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
HEBP1 (HGNC Symbol)
Synonyms
HBP, HEBP
Description
Heme binding protein 1 (HGNC Symbol)
Entrez gene summary
The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]
