Fields »
ABOUT
HELP
BLOG
RUFY3

CANCER ATLAS

Gene description

 RUN and FYVE domain containing 3

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA022952
HPA022970

GENE INFORMATION

Gene name

 RUFY3 (HGNC Symbol)

Synonyms

 KIAA0871, RIPx, Singar1, ZFYVE30

Description

 RUN and FYVE domain containing 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 4

Cytoband

 q13.3

Chromosome location (bp)

 70704204 - 70807315

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000018189 (version 83.38)

Entrez gene

 22902

UniProt

 Q7L099 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7L099

Antibodypedia

 RUFY3 antibodies

PROTEIN BROWSER
RUFY3-001
RUFY3-002
RUFY3-003
RUFY3-004
RUFY3-005
RUFY3-007
RUFY3-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RUFY3-001
ENSP00000226328
ENST00000226328
Q7L099 [Direct mapping]
Protein RUFY3
A0A024RDD7 [Target identity:100%; Query identity:100%]
RUN and FYVE domain containing 3, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007015 [actin filament organization]
GO:0012505 [endomembrane system]
GO:0016020 [membrane]
GO:0030027 [lamellipodium]
GO:0030054 [cell junction]
GO:0030175 [filopodium]
GO:0030335 [positive regulation of cell migration]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030426 [growth cone]
GO:0043204 [perikaryon]
GO:0045773 [positive regulation of axon extension]
GO:0050771 [negative regulation of axonogenesis]
GO:0071437 [invadopodium]
GO:0090316 [positive regulation of intracellular protein transport]
GO:2000114 [regulation of establishment of cell polarity]
Show all
 469 aa
53 kDa 		No 0
RUFY3-002
ENSP00000370394
ENST00000381006
Q7L099 [Direct mapping]
Protein RUFY3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007015 [actin filament organization]
GO:0012505 [endomembrane system]
GO:0016020 [membrane]
GO:0030027 [lamellipodium]
GO:0030054 [cell junction]
GO:0030175 [filopodium]
GO:0030335 [positive regulation of cell migration]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030426 [growth cone]
GO:0043025 [neuronal cell body]
GO:0043204 [perikaryon]
GO:0045773 [positive regulation of axon extension]
GO:0046872 [metal ion binding]
GO:0050770 [regulation of axonogenesis]
GO:0050771 [negative regulation of axonogenesis]
GO:0050772 [positive regulation of axonogenesis]
GO:0071437 [invadopodium]
GO:0090316 [positive regulation of intracellular protein transport]
GO:2000114 [regulation of establishment of cell polarity]
Show all
 620 aa
70.6 kDa 		No 0
RUFY3-003
ENSP00000425400
ENST00000502653
Q7L099 [Direct mapping]
Protein RUFY3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007015 [actin filament organization]
GO:0012505 [endomembrane system]
GO:0016020 [membrane]
GO:0030027 [lamellipodium]
GO:0030054 [cell junction]
GO:0030175 [filopodium]
GO:0030335 [positive regulation of cell migration]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030426 [growth cone]
GO:0043204 [perikaryon]
GO:0045773 [positive regulation of axon extension]
GO:0046872 [metal ion binding]
GO:0050771 [negative regulation of axonogenesis]
GO:0071437 [invadopodium]
GO:0090316 [positive regulation of intracellular protein transport]
GO:2000114 [regulation of establishment of cell polarity]
Show all
 567 aa
64.7 kDa 		No 0
RUFY3-004
ENSP00000425574
ENST00000513597
D6RCQ1 [Direct mapping]
Protein RUFY3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 201 aa
22.2 kDa 		No 0
RUFY3-005
ENSP00000399771
ENST00000417478
Q7L099 [Direct mapping]
Protein RUFY3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007015 [actin filament organization]
GO:0012505 [endomembrane system]
GO:0016020 [membrane]
GO:0030027 [lamellipodium]
GO:0030054 [cell junction]
GO:0030175 [filopodium]
GO:0030335 [positive regulation of cell migration]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030426 [growth cone]
GO:0043204 [perikaryon]
GO:0045773 [positive regulation of axon extension]
GO:0050771 [negative regulation of axonogenesis]
GO:0071437 [invadopodium]
GO:0090316 [positive regulation of intracellular protein transport]
GO:2000114 [regulation of establishment of cell polarity]
Show all
 506 aa
55.9 kDa 		No 0
RUFY3-007
ENSP00000426734
ENST00000503876
D6REM9 [Direct mapping]
Protein RUFY3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 155 aa
17.3 kDa 		No 0
RUFY3-008
ENSP00000426165
ENST00000514898
D6RH24 [Direct mapping]
Protein RUFY3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 98 aa
10 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.