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SYT13

CANCER ATLAS

Gene description

 Synaptotagmin XIII

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA046224

GENE INFORMATION

Gene name

 SYT13 (HGNC Symbol)

Synonyms

 KIAA1427

Description

 Synaptotagmin XIII (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Chromosome

 11

Cytoband

 p11.2

Chromosome location (bp)

 45240301 - 45286319

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000019505 (version 83.38)

Entrez gene

 57586

UniProt

 Q7L8C5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7L8C5

Antibodypedia

 SYT13 antibodies

PROTEIN BROWSER
SYT13-002
SYT13-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SYT13-002
ENSP00000020926
ENST00000020926
Q7L8C5 [Direct mapping]
Synaptotagmin-13
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016192 [vesicle-mediated transport]
GO:0019905 [syntaxin binding]
GO:0030133 [transport vesicle]
GO:0030276 [clathrin binding]
GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter]
Show all
 426 aa
46.9 kDa 		No 0
SYT13-003
ENSP00000432975
ENST00000528101
H0YD47 [Direct mapping]
Synaptotagmin-13
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Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0019905 [syntaxin binding]
GO:0030276 [clathrin binding]
GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter]
Show all
 186 aa
20.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.