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IFT88

GENERAL INFORMATION

Gene name

 IFT88

Gene description

 Intraflagellar transport 88

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 IFT88 (HGNC Symbol)

Synonyms

 D13S1056E, hTg737, MGC26259, Tg737, TTC10

Description

 Intraflagellar transport 88 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 13

Cytoband

 q12.11

Chromosome location (bp)

 20567069 - 20691437

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000032742 (version 83.38)

Entrez gene

 8100

UniProt

 Q13099 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q13099

Antibodypedia

 IFT88 antibodies

PROTEIN BROWSER
IFT88-001
IFT88-002
IFT88-004
IFT88-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
IFT88-001
ENSP00000261632
ENST00000351808
Q13099 [Direct mapping]
Intraflagellar transport protein 88 homolog
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005814 [centriole]
GO:0005929 [cilium]
GO:0006996 [organelle organization]
GO:0030992 [intraciliary transport particle B]
GO:0031514 [motile cilium]
GO:0036064 [ciliary basal body]
GO:0060271 [cilium morphogenesis]
GO:0072372 [primary cilium]
GO:0097542 [ciliary tip]
GO:1902017 [regulation of cilium assembly]
GO:2000785 [regulation of autophagosome assembly]
Show all
 824 aa
93.2 kDa 		No 0
IFT88-002
ENSP00000323580
ENST00000319980
Q13099 [Direct mapping]
Intraflagellar transport protein 88 homolog
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001654 [eye development]
GO:0001822 [kidney development]
GO:0001889 [liver development]
GO:0002080 [acrosomal membrane]
GO:0003382 [epithelial cell morphogenesis]
GO:0005515 [protein binding]
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005929 [cilium]
GO:0005930 [axoneme]
GO:0006996 [organelle organization]
GO:0007219 [Notch signaling pathway]
GO:0007224 [smoothened signaling pathway]
GO:0007288 [sperm axoneme assembly]
GO:0007290 [spermatid nucleus elongation]
GO:0007368 [determination of left/right symmetry]
GO:0007399 [nervous system development]
GO:0007420 [brain development]
GO:0007507 [heart development]
GO:0008104 [protein localization]
GO:0008544 [epidermis development]
GO:0008589 [regulation of smoothened signaling pathway]
GO:0009887 [organ morphogenesis]
GO:0009952 [anterior/posterior pattern specification]
GO:0009953 [dorsal/ventral pattern formation]
GO:0019894 [kinesin binding]
GO:0021513 [spinal cord dorsal/ventral patterning]
GO:0021537 [telencephalon development]
GO:0030324 [lung development]
GO:0030992 [intraciliary transport particle B]
GO:0031016 [pancreas development]
GO:0031122 [cytoplasmic microtubule organization]
GO:0031512 [motile primary cilium]
GO:0031514 [motile cilium]
GO:0032391 [photoreceptor connecting cilium]
GO:0034405 [response to fluid shear stress]
GO:0035058 [nonmotile primary cilium assembly]
GO:0036064 [ciliary basal body]
GO:0036334 [epidermal stem cell homeostasis]
GO:0042384 [cilium assembly]
GO:0042487 [regulation of odontogenesis of dentin-containing tooth]
GO:0042733 [embryonic digit morphogenesis]
GO:0043568 [positive regulation of insulin-like growth factor receptor signaling pathway]
GO:0045598 [regulation of fat cell differentiation]
GO:0048853 [forebrain morphogenesis]
GO:0050680 [negative regulation of epithelial cell proliferation]
GO:0055007 [cardiac muscle cell differentiation]
GO:0060021 [palate development]
GO:0060091 [kinocilium]
GO:0060122 [inner ear receptor stereocilium organization]
GO:0060173 [limb development]
GO:0060259 [regulation of feeding behavior]
GO:0060271 [cilium morphogenesis]
GO:0060411 [cardiac septum morphogenesis]
GO:0060426 [lung vasculature development]
GO:0060914 [heart formation]
GO:0061351 [neural precursor cell proliferation]
GO:0070613 [regulation of protein processing]
GO:0072372 [primary cilium]
GO:0090102 [cochlea development]
GO:0097541 [axonemal basal plate]
GO:0097542 [ciliary tip]
GO:0097546 [ciliary base]
GO:1902017 [regulation of cilium assembly]
GO:2000785 [regulation of autophagosome assembly]
Show all
 833 aa
94.3 kDa 		No 0
IFT88-004
ENSP00000437719
ENST00000537103
F5H6C2 [Direct mapping]
Intraflagellar transport protein 88 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 368 aa
41.9 kDa 		No 0
IFT88-007
ENSP00000374024
ENST00000389373
F6SRW8 [Direct mapping]
Intraflagellar transport protein 88 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 50 aa
5.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.