Cell atlas - SH3YL1 - The Human Protein Atlas

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SH3YL1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	SH3YL1
Gene description	SH3 and SYLF domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	12
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA030927
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus.

Main location

Nucleus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA030927	A-431	Nucleus
	HPA030927	U-2 OS	Nucleus
	HPA030927	U-251 MG	Nucleus

GENE INFORMATION
Gene name	SH3YL1 (HGNC Symbol)
Synonyms	DKFZP586F1318, Ray
Description	SH3 and SYLF domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p25.3
Chromosome location (bp)	217730 - 266398
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000035115 (version 83.38)
Entrez gene	26751
UniProt	Q96HL8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96HL8
Antibodypedia	SH3YL1 antibodies

PROTEIN BROWSER

SH3YL1-001	SH3YL1-002	SH3YL1-003	SH3YL1-004	SH3YL1-005	SH3YL1-011	SH3YL1-016	SH3YL1-019	SH3YL1-020	SH3YL1-021	SH3YL1-023	SH3YL1-029

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SH3YL1-001 ENSP00000348471 ENST00000356150	Q96HL8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0019902 [phosphatase binding] GO:0032587 [ruffle membrane] GO:0035091 [phosphatidylinositol binding] GO:1900027 [regulation of ruffle assembly] Show all	342 aa 37.1 kDa	No	0
SH3YL1-002 ENSP00000384276 ENST00000403712	Q96HL8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0019902 [phosphatase binding] GO:0032587 [ruffle membrane] GO:0035091 [phosphatidylinositol binding] GO:1900027 [regulation of ruffle assembly] Show all	323 aa 34.9 kDa	No	0
SH3YL1-003 ENSP00000384269 ENST00000405430	Q96HL8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0019902 [phosphatase binding] GO:0032587 [ruffle membrane] GO:0035091 [phosphatidylinositol binding] GO:1900027 [regulation of ruffle assembly] Show all	342 aa 37.1 kDa	No	0
SH3YL1-004 ENSP00000384910 ENST00000402632	Q96HL8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0019902 [phosphatase binding] GO:0032587 [ruffle membrane] GO:0035091 [phosphatidylinositol binding] GO:1900027 [regulation of ruffle assembly] Show all	114 aa 11.8 kDa	No	0
SH3YL1-005 ENSP00000383928 ENST00000403658	Q96HL8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0019902 [phosphatase binding] GO:0032587 [ruffle membrane] GO:0035091 [phosphatidylinositol binding] GO:1900027 [regulation of ruffle assembly] Show all	227 aa 25.1 kDa	No	0
SH3YL1-011 ENSP00000385668 ENST00000403657	Q96HL8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0019902 [phosphatase binding] GO:0032587 [ruffle membrane] GO:0035091 [phosphatidylinositol binding] GO:1900027 [regulation of ruffle assembly] Show all	227 aa 25.1 kDa	No	0
SH3YL1-016 ENSP00000410235 ENST00000415368	C9J4Z8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		51 aa 5.5 kDa	No	0
SH3YL1-019 ENSP00000399519 ENST00000431160	H7C1B8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		230 aa 24.6 kDa	No	0
SH3YL1-020 ENSP00000416312 ENST00000451005	H7C499 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	255 aa 27.4 kDa	No	0
SH3YL1-021 ENSP00000474411 ENST00000481932	S4R3I7 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		98 aa 10.9 kDa	No	0
SH3YL1-023 ENSP00000415723 ENST00000454318	C9JJI3 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		59 aa 6.1 kDa	No	0
SH3YL1-029 ENSP00000485824 ENST00000626873	Q96HL8 [Direct mapping] SH3 domain-containing YSC84-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0019902 [phosphatase binding] GO:0032587 [ruffle membrane] GO:0035091 [phosphatidylinositol binding] GO:1900027 [regulation of ruffle assembly] Show all	246 aa 27.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.