Fields »
ABOUT
HELP
BLOG
YTHDC2

CANCER ATLAS

Gene description

 YTH domain containing 2

Protein class

 Enzymes, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA037364

GENE INFORMATION

Gene name

 YTHDC2 (HGNC Symbol)

Synonyms

 DKFZp564A186, FLJ10053, FLJ2194

Description

 YTH domain containing 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q22.2

Chromosome location (bp)

 113513683 - 113595285

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000047188 (version 83.38)

Entrez gene

 64848

UniProt

 Q9H6S0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H6S0

Antibodypedia

 YTHDC2 antibodies

PROTEIN BROWSER
YTHDC2-001
YTHDC2-002
YTHDC2-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
YTHDC2-001
ENSP00000161863
ENST00000161863
Q9H6S0 [Direct mapping]
Probable ATP-dependent RNA helicase YTHDC2
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0004004 [ATP-dependent RNA helicase activity]
GO:0004386 [helicase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0006396 [RNA processing]
GO:0008186 [RNA-dependent ATPase activity]
GO:0034612 [response to tumor necrosis factor]
GO:0044822 [poly(A) RNA binding]
GO:0044829 [positive regulation by host of viral genome replication]
GO:0070063 [RNA polymerase binding]
GO:0070555 [response to interleukin-1]
Show all
 1430 aa
160.2 kDa 		No 0
YTHDC2-002
ENSP00000423101
ENST00000515883
D6RA70 [Direct mapping]
Probable ATP-dependent RNA helicase YTHDC2
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0004004 [ATP-dependent RNA helicase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006396 [RNA processing]
Show all
 739 aa
83 kDa 		No 0
YTHDC2-007
ENSP00000422916
ENST00000514720
D6R9T8 [Direct mapping]
Probable ATP-dependent RNA helicase YTHDC2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0004004 [ATP-dependent RNA helicase activity]
GO:0005737 [cytoplasm]
GO:0006396 [RNA processing]
Show all
 137 aa
15.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.