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SCML1

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GENERAL INFORMATION

Gene name

 SCML1

Gene description

 Sex comb on midleg-like 1 (Drosophila)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleus.

RNA cell category

 Cell line enhanced (U-2197)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleus (approved)

DATA RELIABILITY

Reliability score

 Approved based on 2 antibodies.
HPA035270 , HPA061397
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-2197)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleus.

Main location

 Nucleus (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA035270 A-431 Nucleus
Nucleoli
HPA035270 U-2 OS Nucleoplasm
HPA035270 U-251 MG Nucleus
Nucleoli
HPA061397 HEK 293 Nucleoplasm
HPA061397 PC-3 Nucleoplasm
HPA061397 U-2 OS Nucleoplasm

GENE INFORMATION

Gene name

 SCML1

Synonyms

Description

 Sex comb on midleg-like 1 (Drosophila) (HGNC Symbol)

Entrez gene summary

Chromosome

 X

Cytoband

 p22.13

Chromosome location (bp)

 17737449 - 17754988

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000047634 (version 83.38)

Entrez gene

 6322

UniProt

 Q9UN30 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UN30

Antibodypedia

 SCML1 antibodies

PROTEIN BROWSER
SCML1-001
SCML1-004
SCML1-005
SCML1-006
SCML1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SCML1-001
ENSP00000392587
ENST00000419185
Q5H966 [Direct mapping]
Sex comb on midleg-like protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 148 aa
17.5 kDa 		No 0
SCML1-004
ENSP00000369384
ENST00000380045
Q9UN30 [Direct mapping]
Sex comb on midleg-like protein 1
A0A024RBY0 [Target identity:100%; Query identity:100%]
Sex comb on midleg-like 1 (Drosophila), isoform CRA_c
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0009653 [anatomical structure morphogenesis]
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 208 aa
23.1 kDa 		No 0
SCML1-005
ENSP00000369382
ENST00000380043
Q9UN30 [Direct mapping]
Sex comb on midleg-like protein 1
A0A024RBZ7 [Target identity:100%; Query identity:100%]
Sex comb on midleg-like 1 (Drosophila), isoform CRA_b
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0009653 [anatomical structure morphogenesis]
Show all
 302 aa
34.2 kDa 		No 0
SCML1-006
ENSP00000369380
ENST00000380041
Q9UN30 [Direct mapping]
Sex comb on midleg-like protein 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0009653 [anatomical structure morphogenesis]
Show all
 329 aa
37.4 kDa 		No 0
SCML1-201
ENSP00000381154
ENST00000398080
Q9UN30 [Direct mapping]
Sex comb on midleg-like protein 1
A0A024RBY0 [Target identity:100%; Query identity:100%]
Sex comb on midleg-like 1 (Drosophila), isoform CRA_c
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0009653 [anatomical structure morphogenesis]
Show all
 208 aa
23.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.