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A majority of cancer tissues show moderate nuclear immunoreactivity. Additional cytoplasmic positivity was observed in several melanomas, colorectal, renal cancers along with few cervical and stomach cancers. Several gliomas were strongly stained. Few hepatocellular carcinomas were negative.
GENE INFORMATION
Gene name
COL23A1 (HGNC Symbol)
Synonyms
DKFZp434K0621
Description
Collagen, type XXIII, alpha 1 (HGNC Symbol)
Entrez gene summary
COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008]
Phobius predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)