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Most liver, pancreatic and prostate cancers along with several colorectal, breast and lung cancers showed moderate cytoplasmic positivity. Remaining cancer tissues were in general weakly stained or negative.
GENE INFORMATION
Gene name
OPN3 (HGNC Symbol)
Synonyms
ECPN, encephalopsin, ERO, NMO-1, PPP1R116
Description
Opsin 3 (HGNC Symbol)
Entrez gene summary
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]
