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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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FAM114A2
  • TISSUE

  • CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Family with sequence similarity 114, member A2

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA035869
HPA035870

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most of the cancer tissues exhibited moderate cytoplasmic positivity. Thyroid cancers along with several melanomas and endometrial cancers showed strong staining. Several lymphomas, gliomas, lung, ovarian, cervical and gastric cancers were weakly stained or negative.

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most breast and prostate cancers along with several cases of testicular cancers, lymphomas and melanomas were moderately stained. Cancer cells in general were weakly stained or negative.

GENE INFORMATION

Gene name

FAM114A2 (HGNC Symbol)

Synonyms

133K02, C5orf3

Description

Family with sequence similarity 114, member A2 (HGNC Symbol)

Entrez gene summary

Chromosome

5

Cytoband

q33.2

Chromosome location (bp)

153990128 - 154038936

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000055147 (version 83.38)

Entrez gene

10827

UniProt

Q9NRY5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NRY5

Antibodypedia

FAM114A2 antibodies

PROTEIN BROWSER

«
FAM114A2-001
FAM114A2-004
FAM114A2-005
FAM114A2-006
FAM114A2-007
FAM114A2-008
FAM114A2-009
FAM114A2-010
FAM114A2-011
FAM114A2-012
FAM114A2-014
FAM114A2-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAM114A2-001
ENSP00000341597
ENST00000351797
Q9NRY5 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
GO:0017076 [purine nucleotide binding]
Show all
505 aa
55.5 kDa
No 0
FAM114A2-004
ENSP00000429088
ENST00000520313
E7ESJ7 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
435 aa
48 kDa
No 0
FAM114A2-005
ENSP00000430489
ENST00000522858
Q9NRY5 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
GO:0017076 [purine nucleotide binding]
Show all
505 aa
55.5 kDa
No 0
FAM114A2-006
ENSP00000430384
ENST00000520667
Q9NRY5 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
GO:0017076 [purine nucleotide binding]
Show all
505 aa
55.5 kDa
No 0
FAM114A2-007
ENSP00000429753
ENST00000519808
E5RHI8 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
125 aa
13.3 kDa
No 0
FAM114A2-008
ENSP00000430186
ENST00000522395
E5RGF9 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
210 aa
22.1 kDa
No 0
FAM114A2-009
ENSP00000428551
ENST00000518102
E5RHP2 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
103 aa
11.1 kDa
No 0
FAM114A2-010
ENSP00000429403
ENST00000524246
E5RIK7 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
15 aa
1.7 kDa
No 0
FAM114A2-011
ENSP00000428941
ENST00000522634
E5RK42 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
79 aa
8.5 kDa
No 0
FAM114A2-012
ENSP00000429919
ENST00000517605
E5RH43 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
64 aa
6.9 kDa
No 0
FAM114A2-014
ENSP00000428827
ENST00000523705
E5RFK2 [Direct mapping]
Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
166 aa
17.4 kDa
No 0
FAM114A2-201
ENSP00000479498
ENST00000616320
I6L9D5 [Direct mapping]
FAM114A2 protein; Protein FAM114A2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
249 aa
26.7 kDa
No 0

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