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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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PITHD1
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CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA016936

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most malignant tissues showed weak nuclear positivity or were negative. Several testicular and liver cancers displayed moderate staining.

GENE INFORMATION

Gene name

PITHD1 (HGNC Symbol)

Synonyms

C1orf128, HT014, TXNL1CL

Description

PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

p36.11

Chromosome location (bp)

23778405 - 23788232

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000057757 (version 83.38)

Entrez gene

57095

UniProt

Q9GZP4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9GZP4

Antibodypedia

PITHD1 antibodies

PROTEIN BROWSER

PITHD1-001
PITHD1-002
PITHD1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PITHD1-001
ENSP00000246151
ENST00000246151
Q9GZP4 [Direct mapping]
PITH domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
Show all
211 aa
24.2 kDa
No 0
PITHD1-002
ENSP00000363648
ENST00000374524
X6R8S9 [Direct mapping]
PITH domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
98 aa
11.4 kDa
No 0
PITHD1-003
ENSP00000405957
ENST00000415372
X6RHB9 [Direct mapping]
PITH domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
70 aa
8.1 kDa
No 0

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The Human Protein Atlas project is funded
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