Expression of PRDM6 in cancer - Summary

CANCER ATLAS

Gene description

PR domain containing 6

Protein class

Enzymes, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Glioma

STAINING SUMMARY

HPA030322	HPA030324

GENE INFORMATION
Gene name	PRDM6
Synonyms
Description	PR domain containing 6 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q23.2
Chromosome location (bp)	123089121 - 123194266
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000061455 (version 83.38)
Entrez gene	93166
UniProt	Q9NQX0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NQX0
Antibodypedia	PRDM6 antibodies

PROTEIN BROWSER

PRDM6-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRDM6-001 ENSP00000384725 ENST00000407847	Q9NQX0 [Direct mapping] Putative histone-lysine N-methyltransferase PRDM6 Show all	Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0018024 [histone-lysine N-methyltransferase activity] GO:0022008 [neurogenesis] GO:0034968 [histone lysine methylation] GO:0042803 [protein homodimerization activity] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0051151 [negative regulation of smooth muscle cell differentiation] Show all	595 aa 64.5 kDa	No	0