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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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SBNO2
  • TISSUE

  • CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Strawberry notch homolog 2 (Drosophila)

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA041867

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Hepatocellular carcinomas along with several urothelial, testicular, renal and few pancreatic cancers showed moderate to strong cytoplasmic immunoreactivity. Remaining cancers were weakly stained or negative.

GENE INFORMATION

Gene name

SBNO2 (HGNC Symbol)

Synonyms

FLJ00173, KIAA0963, Sno, Stno

Description

Strawberry notch homolog 2 (Drosophila) (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

1107636 - 1174283

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000064932 (version 83.38)

Entrez gene

22904

UniProt

Q9Y2G9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9Y2G9

Antibodypedia

SBNO2 antibodies

PROTEIN BROWSER

SBNO2-001
SBNO2-002
SBNO2-003
SBNO2-010
SBNO2-011
SBNO2-012

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SBNO2-001
ENSP00000354733
ENST00000361757
Q9Y2G9 [Direct mapping]
Protein strawberry notch homolog 2
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002281 [macrophage activation involved in immune response]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0006351 [transcription, DNA-templated]
GO:0030282 [bone mineralization]
GO:0030316 [osteoclast differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0050727 [regulation of inflammatory response]
GO:0061430 [bone trabecula morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071348 [cellular response to interleukin-11]
GO:0071354 [cellular response to interleukin-6]
GO:0072674 [multinuclear osteoclast differentiation]
GO:0072675 [osteoclast fusion]
GO:1990830 [cellular response to leukemia inhibitory factor]
Show all
1366 aa
150.3 kDa
No 0
SBNO2-002
ENSP00000468520
ENST00000587024
K7ES28 [Direct mapping]
Protein strawberry notch homolog 2
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006355 [regulation of transcription, DNA-templated]
GO:0050727 [regulation of inflammatory response]
Show all
1356 aa
149.1 kDa
No 0
SBNO2-003
ENSP00000400762
ENST00000438103
Q9Y2G9 [Direct mapping]
Protein strawberry notch homolog 2
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002281 [macrophage activation involved in immune response]
GO:0005575 [cellular_component]
GO:0006351 [transcription, DNA-templated]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0050727 [regulation of inflammatory response]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071348 [cellular response to interleukin-11]
GO:0071354 [cellular response to interleukin-6]
GO:1990830 [cellular response to leukemia inhibitory factor]
Show all
1309 aa
144.2 kDa
No 0
SBNO2-010
ENSP00000466861
ENST00000590176
K7ENA9 [Direct mapping]
Protein strawberry notch homolog 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006355 [regulation of transcription, DNA-templated]
GO:0050727 [regulation of inflammatory response]
Show all
128 aa
13.8 kDa
No 0
SBNO2-011
ENSP00000468302
ENST00000587655
K7ERL2 [Direct mapping]
Protein strawberry notch homolog 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006355 [regulation of transcription, DNA-templated]
GO:0050727 [regulation of inflammatory response]
Show all
111 aa
12 kDa
No 0
SBNO2-012
ENSP00000468534
ENST00000590998
K7ENA9 [Direct mapping]
Protein strawberry notch homolog 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006355 [regulation of transcription, DNA-templated]
GO:0050727 [regulation of inflammatory response]
Show all
128 aa
13.8 kDa
No 0

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The Human Protein Atlas project is funded
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