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Weak to moderate cytoplasmic with additional nuclear and/or membranous staining was seen in most malignant cells. Several cases of malignant gliomas, malignant lymphomas, hepatocellular carcinomas, skin and lung cancers were negative.
Several cases of pancreatic cancers and papillary adenocarcinomas of thyroid showed moderate staining. Remaining malignant cells were weakly stained or negative.
P36508 [Direct mapping] Zinc finger protein 76 A0A024RCU3 [Target identity:100%; Query identity:100%] Zinc finger protein 76 (Expressed in testis), isoform CRA_b
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Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014)
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GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0046872 [metal ion binding]
GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0046872 [metal ion binding]