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Most cancer tissues displayed weak to moderate cytoplasmic positivity. A few colorectal cancers were strongly stained. Lymphomas along with several gliomas, endometrial, liver, skin and renal cancers were negative.
GENE INFORMATION
Gene name
NTN1 (HGNC Symbol)
Synonyms
NTN1L
Description
Netrin 1 (HGNC Symbol)
Entrez gene summary
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]