Expression of PDIA5 in cancer - Summary

CANCER ATLAS

Gene description

Protein disulfide isomerase family A, member 5

Protein class

Enzymes, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA030353	HPA030355

GENE INFORMATION
Gene name	PDIA5 (HGNC Symbol)
Synonyms	FLJ30401, PDIR
Description	Protein disulfide isomerase family A, member 5 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q21.1
Chromosome location (bp)	123067062 - 123225227
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000065485 (version 83.38)
Entrez gene	10954
UniProt	Q14554 (UniProt - Evidence at protein level)
neXtProt	NX_Q14554
Antibodypedia	PDIA5 antibodies

PROTEIN BROWSER

PDIA5-001	PDIA5-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PDIA5-001 ENSP00000323313 ENST00000316218	Q14554 [Direct mapping] Protein disulfide-isomerase A5 Show all	Enzymes ENZYME proteins Isomerase MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003756 [protein disulfide isomerase activity] GO:0005515 [protein binding] GO:0005788 [endoplasmic reticulum lumen] GO:0005789 [endoplasmic reticulum membrane] GO:0006457 [protein folding] GO:0016491 [oxidoreductase activity] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0034976 [response to endoplasmic reticulum stress] GO:0036498 [IRE1-mediated unfolded protein response] GO:0044267 [cellular protein metabolic process] GO:0045454 [cell redox homeostasis] GO:0055114 [oxidation-reduction process] Show all	519 aa 59.6 kDa	Yes	0
PDIA5-004 ENSP00000419946 ENST00000484644	C9JY10 [Direct mapping] Protein disulfide-isomerase A5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0034976 [response to endoplasmic reticulum stress] Show all	64 aa 7.3 kDa	No	0