Expression of SLK in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

STE20-like kinase

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA015757

GENE INFORMATION
Gene name	SLK (HGNC Symbol)
Synonyms	KIAA0204, se20-9, STK2
Description	STE20-like kinase (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband
Chromosome location (bp)	103967201 - 104029233
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000065613 (version 83.38)
Entrez gene	9748
UniProt	Q9H2G2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H2G2
Antibodypedia	SLK antibodies

PROTEIN BROWSER

SLK-001	SLK-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLK-001 ENSP00000336824 ENST00000335753	Q9H2G2 [Direct mapping] STE20-like serine/threonine-protein kinase Show all	Enzymes ENZYME proteins Transferases Kinases STE Ser/Thr protein kinases Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0006915 [apoptotic process] GO:0007346 [regulation of mitotic cell cycle] GO:0023014 [signal transduction by protein phosphorylation] GO:0031098 [stress-activated protein kinase signaling cascade] GO:0032147 [activation of protein kinase activity] GO:0042802 [identical protein binding] GO:0042803 [protein homodimerization activity] GO:0042981 [regulation of apoptotic process] GO:0046777 [protein autophosphorylation] GO:0070062 [extracellular exosome] Show all	1204 aa 139 kDa	No	0
SLK-002 ENSP00000358770 ENST00000369755	Q9H2G2 [Direct mapping] STE20-like serine/threonine-protein kinase Show all	Enzymes ENZYME proteins Transferases Kinases STE Ser/Thr protein kinases Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0006915 [apoptotic process] GO:0007346 [regulation of mitotic cell cycle] GO:0023014 [signal transduction by protein phosphorylation] GO:0031098 [stress-activated protein kinase signaling cascade] GO:0032147 [activation of protein kinase activity] GO:0042802 [identical protein binding] GO:0042803 [protein homodimerization activity] GO:0042981 [regulation of apoptotic process] GO:0046777 [protein autophosphorylation] GO:0070062 [extracellular exosome] Show all	1235 aa 142.7 kDa	No	0