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CTNNA2

CANCER ATLAS

Gene description

 Catenin (cadherin-associated protein), alpha 2

Protein class

 Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Glioma

STAINING SUMMARY
CAB037175

GENE INFORMATION

Gene name

 CTNNA2 (HGNC Symbol)

Synonyms

 CAP-R, CT114

Description

 Catenin (cadherin-associated protein), alpha 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p12

Chromosome location (bp)

 79185231 - 80648861

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000066032 (version 83.38)

Entrez gene

 1496

UniProt

 P26232 (UniProt - Evidence at protein level)

neXtProt

 NX_P26232

Antibodypedia

 CTNNA2 antibodies

PROTEIN BROWSER
«
CTNNA2-001
CTNNA2-002
CTNNA2-003
CTNNA2-005
CTNNA2-006
CTNNA2-007
CTNNA2-015
CTNNA2-021
CTNNA2-201
CTNNA2-202
CTNNA2-203
CTNNA2-204
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CTNNA2-001
ENSP00000419295
ENST00000496558
P26232 [Direct mapping]
Catenin alpha-2
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005198 [structural molecule activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0007409 [axonogenesis]
GO:0015629 [actin cytoskeleton]
GO:0016337 [single organismal cell-cell adhesion]
GO:0021942 [radial glia guided migration of Purkinje cell]
GO:0030424 [axon]
GO:0042692 [muscle cell differentiation]
GO:0045296 [cadherin binding]
GO:0048813 [dendrite morphogenesis]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051823 [regulation of synapse structural plasticity]
GO:0060134 [prepulse inhibition]
Show all
 905 aa
100.4 kDa 		No 0
CTNNA2-002
ENSP00000418191
ENST00000466387
P26232 [Direct mapping]
Catenin alpha-2
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005198 [structural molecule activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0007409 [axonogenesis]
GO:0015629 [actin cytoskeleton]
GO:0016337 [single organismal cell-cell adhesion]
GO:0021942 [radial glia guided migration of Purkinje cell]
GO:0030424 [axon]
GO:0042692 [muscle cell differentiation]
GO:0045296 [cadherin binding]
GO:0048813 [dendrite morphogenesis]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051823 [regulation of synapse structural plasticity]
GO:0060134 [prepulse inhibition]
Show all
 905 aa
100.4 kDa 		No 0
CTNNA2-003
ENSP00000384638
ENST00000402739
P26232 [Direct mapping]
Catenin alpha-2
Show all
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005198 [structural molecule activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0007155 [cell adhesion]
GO:0007409 [axonogenesis]
GO:0015629 [actin cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0016337 [single organismal cell-cell adhesion]
GO:0021942 [radial glia guided migration of Purkinje cell]
GO:0030027 [lamellipodium]
GO:0030424 [axon]
GO:0042692 [muscle cell differentiation]
GO:0045296 [cadherin binding]
GO:0048813 [dendrite morphogenesis]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051823 [regulation of synapse structural plasticity]
GO:0060134 [prepulse inhibition]
GO:0097481 [neuronal postsynaptic density]
Show all
 953 aa
105.3 kDa 		No 0
CTNNA2-005
ENSP00000387232
ENST00000409266
B8ZZE7 [Direct mapping]
Catenin alpha-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005913 [cell-cell adherens junction]
GO:0007155 [cell adhesion]
GO:0045296 [cadherin binding]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
Show all
 44 aa
5.1 kDa 		No 0
CTNNA2-006
ENSP00000400105
ENST00000451966
C9J144 [Direct mapping]
Catenin alpha-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005913 [cell-cell adherens junction]
GO:0007155 [cell adhesion]
GO:0045296 [cadherin binding]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
Show all
 66 aa
7.2 kDa 		No 0
CTNNA2-007
ENSP00000387073
ENST00000409971
C9IZ88 [Direct mapping]
Catenin alpha-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005913 [cell-cell adherens junction]
GO:0007155 [cell adhesion]
GO:0045296 [cadherin binding]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
Show all
 117 aa
12.8 kDa 		No 0
CTNNA2-015
ENSP00000386587
ENST00000409550
B9A010 [Direct mapping]
Catenin alpha-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005913 [cell-cell adherens junction]
GO:0007155 [cell adhesion]
GO:0045296 [cadherin binding]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
Show all
 190 aa
21.4 kDa 		No 0
CTNNA2-021
ENSP00000486160
ENST00000629316
P26232 [Direct mapping]
Catenin alpha-2
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005198 [structural molecule activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0007409 [axonogenesis]
GO:0015629 [actin cytoskeleton]
GO:0016337 [single organismal cell-cell adhesion]
GO:0021942 [radial glia guided migration of Purkinje cell]
GO:0030424 [axon]
GO:0042692 [muscle cell differentiation]
GO:0045296 [cadherin binding]
GO:0048813 [dendrite morphogenesis]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051823 [regulation of synapse structural plasticity]
GO:0060134 [prepulse inhibition]
Show all
 860 aa
95.6 kDa 		No 0
CTNNA2-201
ENSP00000341500
ENST00000343114
P26232 [Direct mapping]
Catenin alpha-2
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0007409 [axonogenesis]
GO:0015629 [actin cytoskeleton]
GO:0016337 [single organismal cell-cell adhesion]
GO:0021942 [radial glia guided migration of Purkinje cell]
GO:0030424 [axon]
GO:0042692 [muscle cell differentiation]
GO:0045296 [cadherin binding]
GO:0048813 [dendrite morphogenesis]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051823 [regulation of synapse structural plasticity]
GO:0060134 [prepulse inhibition]
Show all
 584 aa
65.1 kDa 		No 0
CTNNA2-202
ENSP00000355398
ENST00000361291
A0A0A0MRI5 [Direct mapping]
Catenin alpha-2
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005913 [cell-cell adherens junction]
GO:0007155 [cell adhesion]
GO:0045296 [cadherin binding]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
Show all
 569 aa
62.8 kDa 		No 0
CTNNA2-203
ENSP00000441705
ENST00000540488
A0A0A0MTJ6 [Direct mapping]
Catenin alpha-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005913 [cell-cell adherens junction]
GO:0007155 [cell adhesion]
GO:0045296 [cadherin binding]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
Show all
 476 aa
53 kDa 		No 0
CTNNA2-204
ENSP00000444675
ENST00000541047
P26232 [Direct mapping]
Catenin alpha-2
F6KRI5 [Target identity:100%; Query identity:100%]
Catenin alpha 2 isoform CTNNA2b
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0007409 [axonogenesis]
GO:0015629 [actin cytoskeleton]
GO:0016337 [single organismal cell-cell adhesion]
GO:0021942 [radial glia guided migration of Purkinje cell]
GO:0030424 [axon]
GO:0042692 [muscle cell differentiation]
GO:0045296 [cadherin binding]
GO:0048813 [dendrite morphogenesis]
GO:0048854 [brain morphogenesis]
GO:0051015 [actin filament binding]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051823 [regulation of synapse structural plasticity]
GO:0060134 [prepulse inhibition]
Show all
 537 aa
59.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.