Expression of CD84 in cancer - Summary - The Human Protein Atlas

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CD84

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TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

CD84 molecule

Protein class

CD markers, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA070502

GENE INFORMATION
Gene name	CD84 (HGNC Symbol)
Synonyms	hCD84, mCD84, SLAMF5
Description	CD84 molecule (HGNC Symbol)
Entrez gene summary	This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Chromosome	1
Cytoband	q23.3
Chromosome location (bp)	160541095 - 160579516
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000066294 (version 83.38)
Entrez gene	8832
UniProt	Q9UIB8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UIB8
Antibodypedia	CD84 antibodies

PROTEIN BROWSER

CD84-001	CD84-002	CD84-003	CD84-004	CD84-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD84-001 ENSP00000357033 ENST00000368054	Q9UIB8 [Direct mapping] SLAM family member 5 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006952 [defense response] GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules] GO:0007596 [blood coagulation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular exosome] Show all	328 aa 36.9 kDa	Yes	1
CD84-002 ENSP00000357027 ENST00000368048	Q9UIB8 [Direct mapping] SLAM family member 5 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006952 [defense response] GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules] GO:0007596 [blood coagulation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular exosome] Show all	339 aa 38.1 kDa	Yes	1
CD84-003 ENSP00000312367 ENST00000311224	Q9UIB8 [Direct mapping] SLAM family member 5 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006952 [defense response] GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules] GO:0007596 [blood coagulation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular exosome] Show all	345 aa 38.8 kDa	Yes	1
CD84-004 ENSP00000357030 ENST00000368051	Q9UIB8 [Direct mapping] SLAM family member 5 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006952 [defense response] GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules] GO:0007596 [blood coagulation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular exosome] Show all	272 aa 30.5 kDa	Yes	1
CD84-201 ENSP00000442845 ENST00000534968	Q9UIB8 [Direct mapping] SLAM family member 5 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006952 [defense response] GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules] GO:0007596 [blood coagulation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular exosome] Show all	214 aa 24 kDa	Yes	1

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The Human Protein Atlas

The Human Protein Atlas project is funded
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