Expression of HES2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Hes family bHLH transcription factor 2

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Cervical cancer

STAINING SUMMARY

HPA039462

GENE INFORMATION
Gene name	HES2 (HGNC Symbol)
Synonyms	bHLHb40
Description	Hes family bHLH transcription factor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.31
Chromosome location (bp)	6412418 - 6424670
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000069812 (version 83.38)
Entrez gene	54626
UniProt	Q9Y543 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y543
Antibodypedia	HES2 antibodies

PROTEIN BROWSER

HES2-001	HES2-002	HES2-003	HES2-004	HES2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HES2-001 ENSP00000367065 ENST00000377834	Q9Y543 [Direct mapping] Transcription factor HES-2 Show all	Predicted intracellular proteins Transcription factors Basic domains Show all	GO:0003677 [DNA binding] GO:0003690 [double-stranded DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046983 [protein dimerization activity] Show all	173 aa 18.5 kDa	No	0
HES2-002 ENSP00000367068 ENST00000377837	Q9Y543 [Direct mapping] Transcription factor HES-2 Show all	Predicted intracellular proteins Transcription factors Basic domains Show all	GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0046983 [protein dimerization activity] Show all	76 aa 8.6 kDa	No	0
HES2-003 ENSP00000367067 ENST00000377836	Q9Y543 [Direct mapping] Transcription factor HES-2 Show all	Predicted intracellular proteins Transcription factors Basic domains Show all	GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0046983 [protein dimerization activity] Show all	76 aa 8.6 kDa	No	0
HES2-004 ENSP00000465248 ENST00000487437	K7EJN2 [Direct mapping] Transcription factor HES-2 Show all	Predicted intracellular proteins Show all	GO:0046983 [protein dimerization activity] Show all	77 aa 8.4 kDa	No	0
HES2-005 ENSP00000465270 ENST00000489730	K7EJQ0 [Direct mapping] Transcription factor HES-2 Show all	Predicted intracellular proteins Show all	GO:0046983 [protein dimerization activity] Show all	82 aa 9.2 kDa	No	0